a lot of与lots of在意义和用法上相同，都是起形容词作用的词组，后接可数或者不可数名词，相当于many或much。
二者区别
1.lots of和a lot of可以当做定语，即当做many或much那样来使用。因此，谓语动词的数不是依据lot和lots来决定，而是依据of所引导的名词的数来决定。
2.a lot of=lots of表示”许多的“，可以修饰可数名词复数和不可数名词。
3.a lot是表示程度的一个短语，意为”很，非常“。
4.书面语用a lot of较多，口语用lots of较多。
a lot of 例句
1.The boy had a lot of pocket money.
这男孩有许多零用钱。
2.I think this new system has a lot going for it.
我认为这一新体系有许多有利之处。
3.There is a lot of flu going round at the moment .
现在流感传染很广。
4.A road bridge has to carry a lot of traffic .
高架路得承载很多车辆。
5.The strike has caused a lot of misery .
罢工给我们带来了极大的不幸。
lots of用法例句
1.He wrote lots of poems in his life.
他一生中写了许多诗。
2.There are lots of pear trees near the house .
屋子近旁种着许多梨树。
3.There are lots of troubles in the world !
世界上不幸的事真多呀！
4.There will be lots of action around these parts .
这儿战事一定会很频繁。
5.She had lots of friends.
她有许多朋友。